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What is Metformin

1 Corinthians 10:31 – Whether therefore ye eat, or drink, or whatsoever ye do, do all to the glory of God. Make sure to take care of yourself so that you can continue to enjoy yourself and have a good life.

Metformin is a medication that is approved by the U.S. Food and Drug Administration to treat diabetes. Metformin is used to treat high blood sugar levels caused by a type of diabetes called type 2 diabetes, known as diabetes mellitus, or sugar diabetes. According to a study, metformin has been shown to have a similar effect as an insulin-sensitizing agent in type 1 diabetes to the SGLT-2 inhibitors (which are usually taken only by type 2 diabetics as well). I learned — like millions of other people with type 2 diabetes — that metformin does not lower blood sugar right away.

Metformin is considered to be an antihyperglycemic medication, as Metformin reduces the blood glucose concentrations of type II diabetes patients, but does not induce low blood sugar. Metformin generally does not cause hypoglycemia, which leads it to be considered as a unique antidiabetic medication. Metformin, which has been studied in humans since 1950, is a prescription medicine taken to help control diabetes, which comes as a pill. Metformin is available generically and in different brands, both alone and in combination with other medications.

It is also shown to be a useful preventive treatment for those who are at risk for developing type 2 diabetes as well as for people who have pre-diabetes, a precursor to type 2 diabetes, although the FDA has not approved metformin for these uses. The FDA has approved metformin for treatment of only type 2 diabetes, research shows metformin may be useful in a number of other health benefits for people with and without diabetes. Metformin is most commonly used to treat type 2 diabetes, whether alone or combined with other agents, but it is also used off-label as a treatment for prediabetes, gestational diabetes, and PCOS. Over the last 2 decades, metformin has emerged as the primarystay of treatment for type 2 diabetes, and is now the recommended first-line medication to treat the disease in the U.S. and globally.

3 John 1:2 – Beloved, I wish above all things that thou mayest prosper and be in health, even as thy soul prospereth.

Metformin is so effective as the first-line treatment that the American Diabetes Association includes it in its Diabetes Standards of Care. Metformin is still the preferred first-line oral treatment for type 2 diabetes, and is the most commonly prescribed medication to reduce blood glucose levels around the world. Metformin, sold by the brand names Glucophage and others, is a first-line medication to treat Type 2 diabetes, especially for overweight individuals. Metformin is a treatment indicated as an adjunct to diet, exercise, and lifestyle changes, such as weight loss, to improve glucose (blood sugar) control in adults with type 2 diabetes.

Metformin is a biguanide medication used with diet and exercise to improve glucose control in type 2 diabetes mellitus, and used off-label to treat insulin resistance in polycystic ovary syndrome (PCOS). Susan L. Besser says that although it is approved for only the treatment of type 2 diabetes, metformin is used off-label for weight loss, polycystic ovarian syndrome (PCOS), infertility, diabetes prevention, pregnancy complications, and obesity. Many patients with type 1 take Metforminoff-label (with the consent of their doctor) to help control blood sugar, reduce insulin resistance, and even weight loss. If you are someone with type 2 diabetes, taking Metformin is easy, inexpensive, and a powerful way to reduce blood sugar, get better HbA1c results, improve insulin sensitivity, and even lose some weight.

Depending on the severity of your illness, metformin may be used with other medicines to help you manage blood sugars (blood sugar) and improve hemoglobin A1c (HbA1c) levels. Using metformin, along with a type of oral antidiabetic medication called a sulfonylurea, or with insulin, helps to lower your blood sugar when it is too high and helps restore how your body uses food for energy. A note about hypoglycemia When used alone, metformin does not cause hypoglycemia, however, Metformin can intensify the hypoglycemic effects of sulfonylureas and insulin when used together. Metformin is currently not approved for use by U.S. or European regulatory agencies in Type 1, but it is known that people have taken this drug regardless, and many doctors will prescribe it if a person with Type 1 diabetes is overweight.

Metformin is now commonly prescribed as a diabetic drug; however, serious concerns about adverse effects of metformin, particularly ketoacidosis, persist. Other anti-diabetic drugs do not demonstrate similar anticancer activities; therefore, metformins anticancer effects should not be associated with this drugs anti-diabetic activities. If you have severe renal impairment, known hypersensitivity to Metformin, or if you have diabetes with ketoacidosis, you should not take metformin. Using this medicine with any of the following medicines may cause an increased risk for some side effects, but using both medicines may be the best treatment for you.

Gestational Diabetes Some trials suggest that metformin is just as safe and effective as insulin in treating gestational diabetes, and there has been some suggestion that mothers who use metformin instead of insulin might have healthier babies during their neonatal years. New studies are suggesting that metformin could have promise for treating or preventing a wide variety of conditions in patients with and without type 2 diabetes. Studies show metformin can be cardioprotective in patients with diabetes, and is helpful in the presence of stable congestive heart failure.

Antiviral drugs have not worked as well, but metformin improved the blood sugars of these diabetic patients. I expected that metformin would act as insulin in a pill and immediately lower blood sugar levels (about 180 mg/dl at that point).

Psalms 34:4 – I sought the LORD, and he heard me, and delivered me from all my fears.

Metformin is also available in liquid form for children and for those who have trouble swallowing pills. Using a liquid form may be helpful to help people who have a physical or mental difficulty swallowing metformin, or to potentially reduce the number of steps needed to take the medicine. Metformin is also available in 500-mg and 750-mg extended-release formulations. People who have renal problems will take smaller dosages.

Cited Sources

https://www.mayoclinic.org/drugs-supplements/metformin-oral-route/side-effects/drg-20067074?p=1
https://diabetesstrong.com/everything-you-need-to-know-about-metformin/
https://diatribe.org/everything-you-always-wanted-know-about-metformin-were-afraid-ask
https://www.nhs.uk/medicines/metformin/
https://go.drugbank.com/drugs/DB00331
https://www.verywellhealth.com/glumetza-metformin-hydrochloride-oral-5219424
https://www.drugwatch.com/metformin/
https://www.diabeteseducator.org/news/perspectives/aade-blog-details/barbara-walz-rn-bsn-cde/2012/10/04/facts-about-metformin
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4214027/
https://www.rxlist.com/consumer_metformin/drugs-condition.htm